Owen sansom google scholar

Owen sansom h index
Owen Sansom, FRSE., FMedSci is the Director of the Cancer Research UK Beatson Institute He is known for his work determining the molecular hallmarks of.
In 2017 he was elected a Fellow of the Academy of Medical Sciences.

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Prof Owen Sansom FRSE, FMEDSci - Colorectal Cancer and Wnt Signalling

Recent Publications

2025

Centeno PP, Chester C, Ford CA, Ridgway RA, Cammareri P, Jamieson T, Marais R, Campbell AD, Sansom OJ. Epidermal tumour-resistant progenitors require SOX2-driven developmental reprogramming to drive tumorigenesis. bioRxiv. 2025:2025.2001.2023.634502.

Goodwin RJA, Marshall JF, Poulogiannis G, Yuneva M, Brindle KM, Takáts Z, Sansom OJ, Bunch J, Barry ST. Visualizing Cancer Heterogeneity at the Molecular and Cellular Levels: Lessons from Rosetta. Cancer Discov. 2025(1):34-38.

Torang A, Kirov AB, Lammers V, Cameron K, Wouters VM, Jackstadt RF, Lannagan TRM, de Jong JH, Koster J, Sansom O, Medema JP. Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability. Nat Commun. 2025;16(1):264.

2024

Corry SM, Sakhnevych S, Mohamed NE, Malla SB, Byrne R, Young A, Amirkhah R, Bull C, Lees A, Redmond K, Lannagan T, Ridgway R, Taggart FR, Fisher NC, Maughan T, Lawler M, Campbell A, Leedham SJ, Ryan AE, Longley DB

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Professor Owen Sansom

Owen Sansom in the Director of the CRUK Beatson Institute, leads the CRUK Glasgow Cancer Centre and is the Director of the Institute of Cancer Sciences at the University of Glasgow. In 2007 he won the BACR/AstraZeneca Young Scientist Frank Rose Award and in 2012 was elected a Fellow of the Royal Society of Edinburgh and was awarded the Cancer Research UK Future Leaders in Cancer Research prize.

In 2017 he was elected a Fellow of the Academy of Medical Sciences. Owen has published over 275 papers in a research career spanning 20 years. Owen gained his PhD in 2001 working on in vivo models of apoptosis in cancer. Since then, Owen has been instrumental in determining the molecular hallmarks of colorectal cancer (CRC), including showing the roles of the tumour suppressor protein APC and the WNT signalling pathway and the involvement of intestinal stem cells in tumourigenesis.

In 2005, Owen established his own laboratory at the Cancer Research UK Beatson Institute, where he became deputy director in 2010. The Sansom laboratory uses in vivo models and 3D

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School of Cancer Sciences

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Number of items: 346.

2024

Kiourtis, C. et al. (2024) Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ.Nature Cell Biology, (doi: 10.1038/s41556-024-01543-3)(PMID:39537753) (Early Online Publication)

Dannhorn, A. et al. (2024) Morphological and molecular preservation through universal preparation of fresh-frozen tissue samples for multimodal imaging workflows.Nature Protocols, 19(9), pp. 2685-2716. (doi: 10.1038/s41596-024-00987-z)(PMID:38806741)

Lu, Y. et al. (2024) ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma.Cell Reports, 43(7), 114406. (doi: 10.1016/j.celrep.2024.114406)(PMID:38963759)(PMCID:PMC11290356)

Pereira, B. A. et al. (2024) Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.Science Advanc