Heterotopic ossification

Here's what happens when your body tissues turn to bone

“I cannot impress upon you how delicate her skeleton is,” says forensic anthropologist Anna Dhody, a curator at the Mütter Museum. “We kind of think of it like if somebody had taken cotton candy and hardened it slightly.”

Life with FOP is progressively painful and restricted, with hard, jagged points digging into soft tissue and fixing people into one position over time. But people with the disease can still live their lives, especially with help from assistive programs, technology, and caregivers.

Take Orzel, who “lived life fast and furious,” says Dawn Waller, director of the adapted technology program at Inglis House in Philadelphia. This long-term residential care facility for people with physical disabilities is where Orzel called home for 36 years.

She took her wheelchair all around the city, visiting the art museum, shopping for clothes, and drinking wine with friends. She loved bling—earrings, necklaces, bracelets, rings, even tiaras. She amassed a large collection of jewelry, which will be displayed near her sk

Fibrodysplasia ossificans progressiva

Disease in which fibrous connective tissue turns into bone

Medical condition

Fibrodysplasia ossificans progressiva (;[1]abbr.FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification). It is the only known medical condition where one organ system changes into another.[2] It is a severe, disabling disorder with no cure.

FOP is caused by a mutation of the gene ACVR1. The mutation affects the body's repair mechanism, causing fibrous tissue including muscle, tendons, and ligaments to become ossified, either spontaneously or when damaged as the result of trauma. In many cases, otherwise minor injuries can cause joints to become permanently fused as new bone forms, replacing the damaged muscle tissue. This new bone formation (known as "heterotopic ossification") eventually forms a secondary skeleton and progressively restricts the patien

Harry Raymond Eastlack Jr. (1933 - 1973)

HarryRaymondEastlackJr.

Born in Philadelphia, Philadelphia, Pennsylvania, United States

Son of [father unknown] and [mother unknown]

[sibling(s) unknown]

[spouse(s) unknown]

[children unknown]

Died at age 39in Philadelphia, Philadelphia, Pennsylvania, United States

Problems/Questions

Profile last modified | Created 15 Mar 2019

This page has been accessed 443 times.

Biography

Harry Eastlack Jr. is Notable.

Harry was born in 1933. He passed away in 1973.

Sources

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